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Question: Discuss about whether Green Tea is better than Blak Tea in Preventing Cancer. Answer: Introduction PICO QUESTION In young women (P) will drink green tea (I) prevent cancer (O) compared to drinking black tea (C). Tea is normally composed of polyphenols, alkaloids, amino acids, carbohydrates, proteins and volatile organic compounds. The polyphenols are a large group of phytochemicals that contain catechins, which are thought to be responsible for the prevention of cancer. Green tea contains abundant quantity of catechins that is epigallocatechin-3-gallate (EGCG) that is thought to be extremely helpful. In comparison to that black tea have much less concentration of catechins. Although both the kind of tea comes from the same plant Camellia sinesis, Black tea is made by fermentation which green tea does not have to pass through. During the fermentation process many natural benefits are lost in the case of black tea. An extensive search has been performed through various databases, articles and journals in order to address the PICO question. A data in a tabular form has been provided in this report to support the PICO question. Discussion Key words/ search terms/ Phrases Alternative words P Young adult AND Green tea Young adults AND benefits of green tea. Green tea OR cancer prevention. I Green tea Catechins AND cancer prevention Catechins AND reduction of oxidative stress. EGCG OR metastasis. Flavanoids AND anti cancer potential. Polyphenols OR Catechins. Flavanoids OR anticancer potential. C Black tea OR green tea in cancer prevention. Green tea Catechins AND black tea. Components of green tea Or black tea. O Green tea AND Antioxidants Antioxidants OR tumor cell shrinkage Antioxidants AND cancer prevention, antioxidants AND cancer cell shrinkage. CINAHL and MEDLINE have been used to do the research regarding the following PICOT question. Nurses and the health care professionals use the CINAHL database to find out a wide variety of journals. It makes the best use of the research informations. Science literatures have evolved from time to time in terms of their specialization and this website provides us with a vast array of scientific literatures. It is the best database while conducting a review of qualitative evidence. It also provides an advanced search with the limiters. MEDLINE focuses of biomedical and clinical journals. It is one of the most popular and responsible resources on the world wide web. It is an appropriate website for the scholars, physicians and the researchers, nurses. Both CINAHL and MEDLINE have provided with a variety of journals that addresses the PICOT question. Various journals regarding the antioxidant properties of Green tea over black tea had been discussed. ACTION SEARCH MODE RESULTS LIMITERS/EXPANDERS S1 Boolean/ phrase Young* AND Green tea, Cancer* 119 Limiters- Abstract Available; Published Date: 20100101-20171231; English Language; Peer Reviewed. Expander- * Young AND *Cancer S2 Boolean/ phrase Green tea* OR black tea * Green tea OR Cancer prevention 74 Limiters- Abstract Available; Published Date: 20100101-20171231; English Language; Peer Reviewed, Research article. Expander- Cancer*, Prevent* wildcard used. S3 Smart text searching Polyphenols OR Catechins in green tea for preventing cancer. 25 Expanders- Apply related words; Also search within the full text of the articles S4 Boolean/ phrase. Antioxidants* AND metastasis* 25 Full text, Published date: 20120101-20161231 Expanders- Antioxidants*AND Metastasis* wildcard used. S5 Smart text searching- Antioxidants and meta* 12 Limiters- Full text Published Date: 20120101-20161231 Publication: clinical nutrition English Language Peer Reviewed Expanders- Antioxidants* AND meta* S6 Smart text searching-Efficiency of Epi-gallactocatechin-3- gallate in the prevention of cancer 2 Limiters- Application of related words, Full text, English language, peer reviewed, 2014-2017. The PICO question of this assignment is about whether green tea is better than black tea in preventing cancer. Although there are very few evidences that can prove that green tea has any other extra beneficial effects than the black tea, but it can be said that Black tea is made by fermentation which green tea does not have to pass through. During the fermentation process many natural benefits are lost in case of the black tea. Iwasaki, M., Mizusawa, J., Kasuga, Y., Yokoyama, S., Onuma, H., Nishimura, H., ... Tsugane, S. (2014). Green Tea Consumption and Breast Cancer Risk in Japanese Women: A Case-Control Study.Nutrition Cancer,66(1), 57-67. doi:10.1080/01635581.2014.847963 The following research article provides information about the various components of green tea that helps in inhibiting the metastasis of the cancer. It also provides us with the idea of how the antioxidants apply their oxidative radicals on the tumour cells and helps in their destruction. The following journal is a review regarding how green tea consumption has role in minimizing breast cancer. Wang, P., Heber, D., Henning, S. M. (2012). Quercetin Increased the Antiproliferative Activity of Green Tea Polyphenol (-)-Epigallocatechin Gallate in Prostate Cancer Cells.Nutrition Cancer,64(4), 580-587. doi:10.1080/01635581.2012.661514 This reference provides with the information of how the catechin present in the green tea have anticancerous properties. Catechins like Epigallocatechin-3-gallate helps in preventing the metastasis in cancer. Conclusion It can hereby be concluded that green tea has got some really good effects on the health. It has got the antioxidant properties that helps to relieve the oxidative stress and thus helps in inhibiting cancer. Although there are several health benefits of consuming green tea, there are very few research articles that support the raised PICO question. References Connors, S. K., Chornokur, G., Kumar, N. B. (2012). New Insights Into the Mechanisms of Green Tea Catechins in the Chemoprevention of Prostate Cancer.Nutrition Cancer,64(1), 4-22. doi:10.1080/01635581.2012.630158 Iwasaki, M., Mizusawa, J., Kasuga, Y., Yokoyama, S., Onuma, H., Nishimura, H., ... Tsugane, S. (2014). Green Tea Consumption and Breast Cancer Risk in Japanese Women: A Case-Control Study.Nutrition Cancer,66(1), 57-67. doi:10.1080/01635581.2014.847963 Lanfang, W., Xingwei, Z., Jing, L., Li, S., Zhiqiang, L. (2014). Tea consumption and lung cancer risk: A meta-analysis of case-control and cohort studies.Nutrition,30(10), 1122-1127. doi:10.1016/j.nut.2014.02.023 Vance, T. M., Su, J., Fontham, E. H., Koo, S. I., Chun, O. K. (2013). Dietary Antioxidants and Prostate Cancer: A Review.Nutrition Cancer,65(6), 793-801. doi:10.1080/01635581.2013.806672 Wang, P., Heber, D., Henning, S. M. (2012). Quercetin Increased the Antiproliferative Activity of Green Tea Polyphenol (-)-Epigallocatechin Gallate in Prostate Cancer Cells.Nutrition Cancer,64(4), 580-587. doi:10.1080/01635581.2012.661514